My Treatment for Lymphoblastic Lymphoma

My Treatment for Lymphoblastic Lymphoma

I was treated with 2 cycles of “hyper CVAD” chemotherapy with central nervous system prophylaxis. Hyper-CVAD is a common chemotherapy regimen. The agents in the regimen are listed below. After receiving this regimen, you underwent autologous stem cell transplant on September 8, 2004.

CHEMOTHERAPY:

I received the following doses of chemotherapy (doses are based on milligrams per square meter of body surface area – mg/m2):

Drug Name Route Cumulative Dose
Vincristine IV 3.6 mg/m2
Dexamethasone Oral 640 mg/m2
Doxorubicin IV 100 mg/m2Total anthracycline dose =  100 mg/m2First dose at age 21 years
Cyclophosphamide IV 6600 mg/m2
Methotrexate(high dose) IV 2000 mg/m2
Cytarabine(high dose) IV 24,000 mg/m2
Cytarabine Spinal tap 70 mg
Methotrexate Spinal tap 84 mg
Carmustine IV 450 mg/m2
Etoposide IV 1800 mg/m2

 

 

SURGERY:

I had the following surgical procedures as part of my treatment:

May 14, 2004: Hickman catheter placement(central line) by Vijay Trisal, MD at City of Hope

September 22, 2004: Hickman removal by R. David Sanders, PA-C at City of Hope

AUTOLOGOUS STEM CELL TRANSPLANTATION:

I received autologous hematopoietic stem cell transplantation as part of my treatment for lymphoblastic lymphoma.  In autologous stem cell transplantation, my peripheral blood stem cells were collected and then reinfused back into my body after I was treated with chemotherapy.  My infusion date was September 8, 2004.  To prepare my body for the transplant (conditioning), I received BCNU (carmustine) and etoposide (VP-16).  The doses are included in the chemotherapy table above.

TREATMENT COMPLICATIONS:

Chemotherapy was discontinued because of a decrease in my cardiac function.

BLOOD TRANSFUSIONS:

I received multiple blood transfusions during treatment.